Manual de humanidad para encontrar las claves de la felicidad. Therefore, there would be three million people with this problem in Spain ( ENFERMEDADES RARAS, 2009 ENFERMEDADES RARAS. The percentage of population affected by these ailments is estimated at about 7 %. It is further estimated that there may be somewhere between six and eight thousand diseases of this kind, many of them of genetic origin and chronic nature. Rare pathologies are considered to be those whose prevalence rate is less than five per ten thousand inhabitants (EUROPEAN COMMISSION, 2008). The study of less prevalent pathologies, in its various approaches, is gaining prominence in recent years this is mainly due to the activities of the FederaciĆ³n EspaƱola de Enfermedades Raras ( FEDER).
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